Clinical Trials Biostatistics Fellowship




The Canadian Network for Statistical Training in Trials (CANSTAT) is a pan-Canadian, multi-institutional and multi-disciplinary training platform that will provide participants with the technical skills and practical experience needed to become leaders in their field and ensure that clinical trials generate the highest quality evidence to improve the health of Canadians.


Applications are welcomed from individuals with MSc. or PhD in statistics, biostatistics, or a relevant health sciences discipline (e.g., public health or epidemiology) with a strong statistical or quantitative background.


Apply Today! Deadline is March 15.


CNTN Research Symposium 2022


The Canadian Nephrology Trials Network (CNTN) Research Symposium was held on May 9 at the Canadian Society of Nephrology AGM. Co-moderated by Dr. Karthik Tennankore and Hans Vorster, attendees learned about what CNTN has been up to, where they are going, and how to get involved. The session included presentations from Dr. David Collister, Dr. Remi Goupil and Dr. Dylan MacKay.

Read CNTN Research Symposium Lay Summaries


Get Involved: Cognition in Chronic Kidney Disease: A Delphi study to identify stakeholder perspectives on relevant research priorities

You are invited to give your opinion on the top three
most important research questions on cognition
in people with Chronic Kidney Disease.


Cognition (the ability to remember, learn new things, focus, and/or make everyday life decisions) has been identified as a top research priority for people with Chronic Kidney Disease. The aim of this survey is to find out what specific research questions about cognition are important to people living with kidney disease, their family members, as well as researchers, clinicians, and decision makers. This will help guide future research in Chronic Kidney Disease.


The questions you identify can be for any stage of Chronic Kidney Disease (non-dialysis Chronic Kidney Disease, dialysis, or transplant) or modality (peritoneal dialysis, in-centre/home hemodialysis) so please be specific with your questions. For example: What is the role of exercise in improving cognition in people who do peritoneal dialysis?


There are no right or wrong and answers. Further information can be found in the Research Participant Information and Consent Statement.


This survey is voluntary, and all responses will be kept secure; responses will be stripped of email addresses prior to analyses. Your participation will involve completing three survey rounds over the next few months in order to reach consensus. Each round will take approximately 10- 15 minutes to complete. Please complete all three rounds. All participants who complete the surveys will receive a report of the final results.

Completing the survey implies that you have consented to participate.


If you have any questions about the research now or later, please contact the Principal Investigator, Dr. Clara Bohm at or the Research Coordinator, Oksana Harasemiw at or 1-204-632-3541.


Click on the following link or copy and paste the URL below into your internet browser:





Watch Now: Innovative Clinical Trials

Pragmatic cluster randomized trials held at dialysis facilities present complex and interesting ethical issues.  This training module, which was modified from the publication Ethical Issues In Pragmatic Cluster-Randomized Trials In Dialysis Facilities, (American Journal of Kidney Diseases, June 19, 2019), was designed provide you, the viewer, with a clear understanding of ethical issues that need to be addressed in such pragmatic cluster randomized trials. The research team conducted empirical studies and ethical analyses to provide expert guidance for the ethical design and conduct of pragmatic CRTs in dialysis facilities.
This work is part of a larger research project, titled “Integrated Platform for Innovative Pragmatic Cluster-Randomized Registry Trials in Hemodialysis,” which focuses on improving the experiences, outcomes, and healthcare of patients receiving hemodialysis. Conducted by an interdisciplinary research team including patient partners, this project has brought together expertise and health data assets onto an integrated platform to conduct innovative pragmatic registry trials in hemodialysis, and to translate these comparative-effectiveness trials into better practice.

International Consensus Meeting

In October 2020, Kidney International published the International Consensus Definitions of Clinical Trial Outcomes for Kidney Failure: 2020 developed from the 1st International Consensus Meeting on Defining Kidney Failure in Clinical Trials hosted by the ISN in Vancouver, Canada.

The event included Can-SOLVE CKD and CNTN patient partners.

The paper has been summarized into a slide deck and user guide for developing clinical trial protocols. Click on the link to download the PDF and Powerpoint slides.

For more information

Innovative Pragmatic Cluster-Randomized Registry Trials to Improve Hemodialysis Care

Earlier this year, a multidisciplinary team of 9 patients, 74 clinicians/health administrators, 5 policymakers, and 43 researchers, partnering across 13 Universities, 7 SPOR-funded entities, 6 health data organizations, 4 provincial renal agencies, 3 health charities, and 3 companies received a renewal of a CIHR SPOR Innovative Clinical Trial Multi-Year Grant.

CNTN will be supporting the activities of this grant in several ways, including posting new resources to build capacity and promote pragmatic trials in Canada.

Recently, as a part of this grant, Dr. Amit Garg, along with Drs. Merrick Zwarenstein and Ahmed Al-Jaishi spoke about pragmatic trials at the NIH Collaboratory’s Rethinking Clinical Trials Grand Rounds. During their presentation, they discussed some of the defining differences between pragmatic and explanatory trials using an ongoing hemodialysis temperature trial (MyTEMP) as an example.

Read about the MyTEMP trial:

View the presentation:


The Do’s and Don’ts of Patient Engagement

Patient engagement is a relatively new way of conducting research in Canada and many researchers are probably still wondering how to do it well. Dr. Simon Hatcher and his team at the Ottawa Hospital developed a graphic novel style tip sheet, “Top 10 Recommendations for Researchers Working with Lived Experience Partners“.

The comic was created by people with lived experience of suicide at the REFLECT research forum which brought together patients and caregivers as well as suicide prevention researchers, trainees and policy-makers.

The top 10 recommendations are:

  1. Use common and clear language
  2. Allow for customization to patient partner’s needs. Be flexible.
  3. Be authentic in the approach to patient-oriented research. Avoid tokenism.
  4. Define roles. Invite and acknowledge everyone’s contributions.
  5. Balance power dynamics.
  6. Invite patient partners to do more than what they are recruited for.
  7. Compensate fairly and as a matter of course. Reimburse expenses.
  8. Build relationships through honesty and trust.
  9. Ensure governance through integrity and accountability.
  10. Establish and encourage continuous communication and feedback.